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Adipose Tissue-Derived Mesenchymal Stem Cells Extend the Lifespan and Enhance Liver Function in Hepatocyte Organoids

In this study, we generated hepatocyte organoids (HOs) using frozen-thawed primary hepatocytes (PHs) within a three-dimensional (3D) Matrigel dome culture in a porcine model. Previously studied hepatocyte organoid analogs, spheroids, or hepatocyte aggregates created using PHs in 3D culture systems h...

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Detalles Bibliográficos
Autores principales: Ock, Sun A, Kim, Seo-Yeon, Ju, Won Seok, Kim, Young-Im, Wi, Ha-Yeon, Lee, Poongyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607770/
https://www.ncbi.nlm.nih.gov/pubmed/37895114
http://dx.doi.org/10.3390/ijms242015429