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Evaluation of Antifungal Selective Toxicity Using Candida glabrata ERG25 and Human SC4MOL Knock-In Strains

With only four classes of antifungal drugs available for the treatment of invasive systemic fungal infections, the number of resistant fungi is increasing, highlighting the urgent need for novel antifungal drugs. Ergosterol, an essential component of cell membranes, and its synthetic pathway have be...

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Detalles Bibliográficos
Autores principales: Nakano, Keiko, Okamoto, Michiyo, Takahashi-Nakaguchi, Azusa, Sasamoto, Kaname, Yamaguchi, Masashi, Chibana, Hiroji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607794/
https://www.ncbi.nlm.nih.gov/pubmed/37888291
http://dx.doi.org/10.3390/jof9101035