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The Dual-Mode Transition of Myofibroblasts Derived from Hepatic Stellate Cells in Liver Fibrosis

Hepatic stellate cells (HSCs) are the key promoters of liver fibrosis. In response to liver-fibrosis-inducing factors, HSCs express alpha smooth muscle actin (α-SMA) and obtain myofibroblast phenotype. Collagen secretion and high expression of α-SMA with related high cell tension and migration limit...

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Detalles Bibliográficos
Autores principales: Yan, Mengchao, Xie, Ye, Yao, Jia, Li, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607848/
https://www.ncbi.nlm.nih.gov/pubmed/37895138
http://dx.doi.org/10.3390/ijms242015460