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T Cell Receptor Chain Centricity: The Phenomenon and Potential Applications in Cancer Immunotherapy

T cells are crucial players in adaptive anti-cancer immunity. The gene modification of T cells with tumor antigen-specific T cell receptors (TCRs) was a milestone in personalized cancer immunotherapy. TCR is a heterodimer (either α/β or γ/δ) able to recognize a peptide antigen in a complex with self...

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Detalles Bibliográficos
Autores principales: Kalinina, Anastasiia A., Khromykh, Ludmila M., Kazansky, Dmitry B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607890/
https://www.ncbi.nlm.nih.gov/pubmed/37894892
http://dx.doi.org/10.3390/ijms242015211