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T Cell Receptor Chain Centricity: The Phenomenon and Potential Applications in Cancer Immunotherapy
T cells are crucial players in adaptive anti-cancer immunity. The gene modification of T cells with tumor antigen-specific T cell receptors (TCRs) was a milestone in personalized cancer immunotherapy. TCR is a heterodimer (either α/β or γ/δ) able to recognize a peptide antigen in a complex with self...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607890/ https://www.ncbi.nlm.nih.gov/pubmed/37894892 http://dx.doi.org/10.3390/ijms242015211 |