The RANK–RANKL–OPG System: A Multifaceted Regulator of Homeostasis, Immunity, and Cancer

The RANK–RANKL–OPG system is a complex signaling pathway that plays a critical role in bone metabolism, mammary epithelial cell development, immune function, and cancer. RANKL is a ligand that binds to RANK, a receptor expressed on osteoclasts, dendritic cells, T cells, and other cells. RANKL signal...

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Detalles Bibliográficos
Autores principales: De Leon-Oliva, Diego, Barrena-Blázquez, Silvestra, Jiménez-Álvarez, Laura, Fraile-Martinez, Oscar, García-Montero, Cielo, López-González, Laura, Torres-Carranza, Diego, García-Puente, Luis M., Carranza, Sara T., Álvarez-Mon, Miguel Ángel, Álvarez-Mon, Melchor, Diaz, Raul, Ortega, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608105/
https://www.ncbi.nlm.nih.gov/pubmed/37893470
http://dx.doi.org/10.3390/medicina59101752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608105/
https://www.ncbi.nlm.nih.gov/pubmed/37893470
http://dx.doi.org/10.3390/medicina59101752

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