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Bioinformatic Analysis of Recurrent Genomic Alterations and Corresponding Pathway Alterations in Ewing Sarcoma

Ewing Sarcoma (ES) is an aggressive, mesenchymal malignancy associated with a poor prognosis in the recurrent or metastatic setting with an estimated overall survival (OS) of <30% at 5 years. ES is characterized by a balanced, reciprocal chromosomal translocation involving the EWSR1 RNA-binding p...

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Detalles Bibliográficos
Autores principales: Rock, Adam, Uche, An, Yoon, Janet, Agulnik, Mark, Chow, Warren, Millis, Sherri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608227/
https://www.ncbi.nlm.nih.gov/pubmed/37888109
http://dx.doi.org/10.3390/jpm13101499