Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations in an Unstructured Cytoplasmic Loop

The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and the development of gout. In this work, we have analyzed the effects of selected variants, residing in a structurally unresolved cytoplasmic r...

Descripción completa

Detalles Bibliográficos
Autores principales: Mózner, Orsolya, Zámbó, Boglárka, Bartos, Zsuzsa, Gergely, Anna, Szabó, Kata Sára, Jezsó, Bálint, Telbisz, Ágnes, Várady, György, Homolya, László, Hegedűs, Tamás, Sarkadi, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608301/
https://www.ncbi.nlm.nih.gov/pubmed/37887994
http://dx.doi.org/10.3390/membranes13100822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608301/
https://www.ncbi.nlm.nih.gov/pubmed/37887994
http://dx.doi.org/10.3390/membranes13100822

Ejemplares similares