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Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations in an Unstructured Cytoplasmic Loop
The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and the development of gout. In this work, we have analyzed the effects of selected variants, residing in a structurally unresolved cytoplasmic r...
Autores principales: | Mózner, Orsolya, Zámbó, Boglárka, Bartos, Zsuzsa, Gergely, Anna, Szabó, Kata Sára, Jezsó, Bálint, Telbisz, Ágnes, Várady, György, Homolya, László, Hegedűs, Tamás, Sarkadi, Balázs |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608301/ https://www.ncbi.nlm.nih.gov/pubmed/37887994 http://dx.doi.org/10.3390/membranes13100822 |
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