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Organic Synthesis of New Secosteroids from Fucosterol, Its Intestinal Absorption by Caco-2 Cells, and Simulation of the Biological Activities of Vitamin D

We previously examined the cellular uptake of six types of vitamin D in human intestinal Caco-2 cells. Since vitamins D(5)–D(7) were commercially unavailable, we synthesized these compounds organically before studying them. This process led us to understand that new secosteroids could be generated a...

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Detalles Bibliográficos
Autores principales: Komba, Shiro, Hase, Megumi, Kotake-Nara, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608315/
https://www.ncbi.nlm.nih.gov/pubmed/37888475
http://dx.doi.org/10.3390/md21100540