Mining Xanthine Oxidase Inhibitors from an Edible Seaweed Pterocladiella capillacea by Using In Vitro Bioassays, Affinity Ultrafiltration LC-MS/MS, Metabolomics Tools, and In Silico Prediction

The prevalence of gout and the adverse effects of current synthetic anti-gout drugs call for new natural and effective xanthine oxidase (XOD) inhibitors to target this disease. Based on our previous finding that an edible seaweed Pterocladiella capillacea extract inhibits XOD, XOD-inhibitory and ant...

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Detalles Bibliográficos
Autores principales: Wang, Yawen, Zhou, Longjian, Chen, Minqi, Liu, Yayue, Yang, Yu, Lu, Tiantian, Ban, Fangfang, Hu, Xueqiong, Qian, Zhongji, Hong, Pengzhi, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608504/
https://www.ncbi.nlm.nih.gov/pubmed/37888437
http://dx.doi.org/10.3390/md21100502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608504/
https://www.ncbi.nlm.nih.gov/pubmed/37888437
http://dx.doi.org/10.3390/md21100502

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