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Effect of Fusidic Acid and Some Nitrogen-Containing Derivatives on Liposomal and Mitochondrial Membranes

The paper assesses the membranotropic action of the natural antibiotic fusidic acid (FA) and its derivatives. It was found that a FA analogue with ethylenediamine moiety (derivative 2), in contrast to native FA and 3,11-dioxime analogue (derivative 1), is able to increase the mobility of the lipid b...

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Detalles Bibliográficos
Autores principales: Dubinin, Mikhail V., Ilzorkina, Anna I., Salimova, Elena V., Landage, Manish S., Khoroshavina, Ekaterina I., Gudkov, Sergey V., Belosludtsev, Konstantin N., Parfenova, Lyudmila V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608686/
https://www.ncbi.nlm.nih.gov/pubmed/37888007
http://dx.doi.org/10.3390/membranes13100835