Extending the Affinity Range of Weak Affinity Chromatography for the Identification of Weak Ligands Targeting Membrane Proteins

The identification of weak-affinity ligands targeting membrane proteins is of great interest in Fragment-Based Drug Design (FBDD). Recently, miniaturized weak affinity chromatography (WAC) has been proposed as a valuable tool to study interactions between small ligands and wild-type membrane protein...

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Detalles Bibliográficos
Autores principales: Deloche, Adrien, Vidal, François-Xavier, Jammas, Lucile, Wagner, Renaud, Dugas, Vincent, Demesmay, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608817/
https://www.ncbi.nlm.nih.gov/pubmed/37894592
http://dx.doi.org/10.3390/molecules28207113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608817/
https://www.ncbi.nlm.nih.gov/pubmed/37894592
http://dx.doi.org/10.3390/molecules28207113

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