LRRC25 Inhibits IFN-γ Secretion by Microglia to Negatively Regulate Anti-Tuberculosis Immunity in Mice

Background: Leucine-rich repeat-containing protein-25 (LRRC25) can degrade the ISG15 gene in virus-infected cells and prevent overactivation of the type Ⅰ IFN pathway. However, the role of LRRC25 in bacterial infection is still unclear. In this pursuit, the present study aimed to explore the regulat...

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Detalles Bibliográficos
Autores principales: Sheng, Gang, Chu, Hongqian, Duan, Huijuan, Wang, Wenjing, Tian, Na, Liu, Dingyi, Sun, Hong, Sun, Zhaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608824/
https://www.ncbi.nlm.nih.gov/pubmed/37894158
http://dx.doi.org/10.3390/microorganisms11102500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608824/
https://www.ncbi.nlm.nih.gov/pubmed/37894158
http://dx.doi.org/10.3390/microorganisms11102500

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