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Pyrrole-Based Enaminones as Building Blocks for the Synthesis of Indolizines and Pyrrolo[1,2-a]pyrazines Showing Potent Antifungal Activity

As a new approach, pyrrolo[1,2-a]pyrazines were synthesized through the cyclization of 2-formylpyrrole-based enaminones in the presence of ammonium acetate. The enaminones were prepared with a straightforward method, reacting the corresponding alkyl 2-(2-formyl-1H-pyrrol-1-yl)acetates, 2-(2-formyl-1...

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Detalles Bibliográficos
Autores principales: Miranda-Sánchez, Diter, Escalante, Carlos H., Andrade-Pavón, Dulce, Gómez-García, Omar, Barrera, Edson, Villa-Tanaca, Lourdes, Delgado, Francisco, Tamariz, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608852/
https://www.ncbi.nlm.nih.gov/pubmed/37894702
http://dx.doi.org/10.3390/molecules28207223