Marine-Derived Compounds for CDK5 Inhibition in Cancer: Integrating Multi-Stage Virtual Screening, MM/GBSA Analysis and Molecular Dynamics Investigations

Cyclin-dependent kinase 5 (CDK5) plays a crucial role in various biological processes, including immune response, insulin secretion regulation, apoptosis, DNA (deoxyribonucleic acid) damage response, epithelial−mesenchymal transition (EMT), cell migration and invasion, angiogenesis, and myogenesis....

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Detalles Bibliográficos
Autores principales: Shoaib, Tagyedeen H., Almogaddam, Mohammed A., Andijani, Yusra Saleh, Saib, Samaher Ahmad, Almaghrabi, Najwa Mahmoud, Elyas, Abdulaziz Fahad, Azzouni, Rahmah Yasin, Awad, Ehda Ahmad, Mohamed, Shaimaa G. A., Mohamed, Gamal A., Ibrahim, Sabrin R. M., Hussein, Hazem G. A., Osman, Wadah, Ashour, Ahmed, Sherif, Asmaa E., Alzain, Abdulrahim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608970/
https://www.ncbi.nlm.nih.gov/pubmed/37887415
http://dx.doi.org/10.3390/metabo13101090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608970/
https://www.ncbi.nlm.nih.gov/pubmed/37887415
http://dx.doi.org/10.3390/metabo13101090

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