Enzymatic Cleavage of Stx2a in the Gut and Identification of Pancreatic Elastase and Trypsin as Possible Main Cleavers

Shiga toxins (Stxs), especially the Stx2a subtype, are the major virulence factors involved in enterohemorrhagic Escherichia coli (EHEC)-associated hemolytic uremic syndrome (eHUS), a life-threatening disease causing acute kidney injury, especially in children. After oral transmission and colonizati...

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Detalles Bibliográficos
Autores principales: Kellnerová, Sára, Huber, Silke, Massri, Mariam, Fleischer, Verena, Losso, Klemens, Sarg, Bettina, Kremser, Leopold, Talasz, Heribert, He, Xiaohua, Varrone, Elisa, Brigotti, Maurizio, Ardissino, Gianluigi, Orth-Höller, Dorothea, Würzner, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609011/
https://www.ncbi.nlm.nih.gov/pubmed/37894145
http://dx.doi.org/10.3390/microorganisms11102487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609011/
https://www.ncbi.nlm.nih.gov/pubmed/37894145
http://dx.doi.org/10.3390/microorganisms11102487

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