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Solubility and Thermodynamic Analysis of Isotretinoin in Different (DMSO + Water) Mixtures

The solubility and solution thermodynamics of isotretinoin (ITN) (3) in numerous {dimethyl sulfoxide (DMSO) (1) + water (H(2)O) (2)} combinations were studied at 298.2–318.2 K under fixed atmospheric pressure of 101.1 kPa. A shake flask methodology was used to determine ITN solubility, and correlati...

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Detalles Bibliográficos
Autores principales: Shakeel, Faiyaz, Haq, Nazrul, Alshehri, Sultan, Alenazi, Miteb, Alwhaibi, Abdulrahman, Alsarra, Ibrahim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609013/
https://www.ncbi.nlm.nih.gov/pubmed/37894589
http://dx.doi.org/10.3390/molecules28207110