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In Vivo Trafficking of the Anticancer Drug Tris(8-Quinolinolato) Gallium (III) (KP46) by Gallium-68/67 PET/SPECT Imaging

KP46 (tris(hydroxyquinolinato)gallium(III)) is an experimental, orally administered anticancer drug. Its absorption, delivery to tumours, and mode of action are poorly understood. We aimed to gain insight into these issues using gallium-67 and gallium-68 as radiotracers with SPECT and PET imaging in...

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Detalles Bibliográficos
Autores principales: Darwesh, Afnan M. F., Imberti, Cinzia, Bartnicka, Joanna J., Al-Salemee, Fahad, Blower, Julia E., Rigby, Alex, Bordoloi, Jayanta, Griffiths, Alex, Ma, Michelle T., Blower, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609081/
https://www.ncbi.nlm.nih.gov/pubmed/37894695
http://dx.doi.org/10.3390/molecules28207217