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The Sterol Transporter Npc2c Controls Intestinal Stem Cell Mitosis and Host–Microbiome Interactions in Drosophila

Cholesterol is necessary for all cells to function. The intracellular cholesterol transporters Npc1 and Npc2 control sterol trafficking and their malfunction leads to Neimann–Pick Type C disease, a rare disorder affecting the nervous system and the intestine. Unlike humans that encode single Npc1 an...

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Detalles Bibliográficos
Autores principales: Neophytou, Constantina, Soteriou, Euripides, Pitsouli, Chrysoula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609107/
https://www.ncbi.nlm.nih.gov/pubmed/37887409
http://dx.doi.org/10.3390/metabo13101084