Inhibitory Mechanisms of Lekethromycin in Dog Liver Cytochrome P450 Enzymes Based on UPLC-MS/MS Cocktail Method

Lekethromycin (LKMS) is a synthetic macrolide compound derivative intended for use as a veterinary medicine. Since there have been no in vitro studies evaluating its potential for drug–drug interactions related to cytochrome P450 (CYP450) enzymes, the effect of the inhibitory mechanisms of LKMS on C...

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Detalles Bibliográficos
Autores principales: Sun, Pan, Cao, Yuying, Qiu, Jicheng, Kong, Jingyuan, Zhang, Suxia, Cao, Xingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609143/
https://www.ncbi.nlm.nih.gov/pubmed/37894672
http://dx.doi.org/10.3390/molecules28207193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609143/
https://www.ncbi.nlm.nih.gov/pubmed/37894672
http://dx.doi.org/10.3390/molecules28207193

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