Identification of the Biosynthetic Gene Cluster of New Piperazic Acid-Containing Lipopeptides with Cytotoxic Activity in the Genome of Marine Streptomyces PHM034

Three novel lipopeptides, PM130391 (1), PM130392 (2), and PM140293 (3) were obtained from cultures of Streptomyces tuirus PHM034 isolated from a marine sediment. Structural elucidation of the three compounds showed they belong to the nonribosomal peptides family, and they all contain an acylated ala...

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Detalles Bibliográficos
Autores principales: Ceniceros, Ana, Cañedo, Librada, Méndez, Carmen, Olano, Carlos, Schleissner, Carmen, Cuevas, Carmen, de la Calle, Fernando, Salas, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609185/
https://www.ncbi.nlm.nih.gov/pubmed/37887416
http://dx.doi.org/10.3390/metabo13101091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609185/
https://www.ncbi.nlm.nih.gov/pubmed/37887416
http://dx.doi.org/10.3390/metabo13101091

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