Inhibition of GCN2 Reveals Synergy with Cell-Cycle Regulation and Proteostasis

The integrated stress response is a signaling network comprising four branches, each sensing different cellular stressors, converging on the phosphorylation of eIF2α to downregulate global translation and initiate recovery. One of these branches includes GCN2, which senses cellular amino acid insuff...

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Detalles Bibliográficos
Autores principales: Gauthier-Coles, Gregory, Rahimi, Farid, Bröer, Angelika, Bröer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609202/
https://www.ncbi.nlm.nih.gov/pubmed/37887389
http://dx.doi.org/10.3390/metabo13101064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609202/
https://www.ncbi.nlm.nih.gov/pubmed/37887389
http://dx.doi.org/10.3390/metabo13101064

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