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Inhibition of GCN2 Reveals Synergy with Cell-Cycle Regulation and Proteostasis
The integrated stress response is a signaling network comprising four branches, each sensing different cellular stressors, converging on the phosphorylation of eIF2α to downregulate global translation and initiate recovery. One of these branches includes GCN2, which senses cellular amino acid insuff...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609202/ https://www.ncbi.nlm.nih.gov/pubmed/37887389 http://dx.doi.org/10.3390/metabo13101064 |