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Evaluation of the Cytotoxic and Antiviral Effects of Small Molecules Selected by In Silico Studies as Inhibitors of SARS-CoV-2 Cell Entry

The spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relies on host cell surface glycans to facilitate interaction with the angiotensin-converting enzyme 2 (ACE-2) receptor. This interaction between ACE2 and the spike protein is a gateway for the virus to enter host...

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Detalles Bibliográficos
Autores principales: Carvalhal, Francisca, Magalhães, Ana Cristina, Rebelo, Rita, Palmeira, Andreia, Resende, Diana I. S. P., Durães, Fernando, Maia, Miguel, Xavier, Cristina P. R., Pereira, Luísa, Sousa, Emília, Correia-da-Silva, Marta, Vasconcelos, M. Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609270/
https://www.ncbi.nlm.nih.gov/pubmed/37894682
http://dx.doi.org/10.3390/molecules28207204