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Radiosynthesis and Early Evaluation of a Positron Emission Tomography Imaging Probe [(18)F]AGAL Targeting Alpha-Galactosidase A Enzyme for Fabry Disease

Success of gene therapy relies on the durable expression and activity of transgene in target tissues. In vivo molecular imaging approaches using positron emission tomography (PET) can non-invasively measure magnitude, location, and durability of transgene expression via direct transgene or indirect...

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Detalles Bibliográficos
Autores principales: Lohith, Talakad G., Kaittanis, Charalambos, Belanger, Anthony P., Ahn, Shin Hye, Sandoval, Phil, Cohen, Lawrence, Rajarshi, Girija, Ruangsiriluk, Wanida, Islam, Rizwana, Winkelmann, Christopher T., McQuade, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609273/
https://www.ncbi.nlm.nih.gov/pubmed/37894622
http://dx.doi.org/10.3390/molecules28207144