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Radiosynthesis and Early Evaluation of a Positron Emission Tomography Imaging Probe [(18)F]AGAL Targeting Alpha-Galactosidase A Enzyme for Fabry Disease
Success of gene therapy relies on the durable expression and activity of transgene in target tissues. In vivo molecular imaging approaches using positron emission tomography (PET) can non-invasively measure magnitude, location, and durability of transgene expression via direct transgene or indirect...
Autores principales: | Lohith, Talakad G., Kaittanis, Charalambos, Belanger, Anthony P., Ahn, Shin Hye, Sandoval, Phil, Cohen, Lawrence, Rajarshi, Girija, Ruangsiriluk, Wanida, Islam, Rizwana, Winkelmann, Christopher T., McQuade, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609273/ https://www.ncbi.nlm.nih.gov/pubmed/37894622 http://dx.doi.org/10.3390/molecules28207144 |
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