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A Simple and Fast Method for the Formation and Downstream Processing of Cancer-Cell-Derived 3D Spheroids: An Example Using Nicotine-Treated A549 Lung Cancer 3D Spheres

Although 2D in vitro cancer cell cultures have been used for decades as a first line-of-research tool to investigate antitumoral drugs and treatments, their use presents many drawbacks, including the poor resemblance of such cultures to the characteristics of in vivo tumors. To mitigate these drawba...

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Detalles Bibliográficos
Autores principales: Papapostolou, Irida, Bochen, Florian, Peinelt, Christine, Maldifassi, Maria Constanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609300/
https://www.ncbi.nlm.nih.gov/pubmed/37888026
http://dx.doi.org/10.3390/mps6050094