Mutation Analysis in Regulator DNA-Binding Regions for Antimicrobial Efflux Pumps in 17,000 Pseudomonas aeruginosa Genomes

Mutations leading to upregulation of efflux pumps can produce multiple drug resistance in the pathogen Pseudomonas aeruginosa. Changes in their DNA binding regions, i.e., palindromic operators, can compromise pump depression and subsequently enhance resistance against several antibacterials and bioc...

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Detalles Bibliográficos
Autores principales: Pérez-Vázquez, María, López-Causapé, Carla, Corral-Lugo, Andrés, McConnell, Michael J., Oteo-Iglesias, Jesús, Oliver, Antonio, Martín-Galiano, Antonio J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609311/
https://www.ncbi.nlm.nih.gov/pubmed/37894144
http://dx.doi.org/10.3390/microorganisms11102486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609311/
https://www.ncbi.nlm.nih.gov/pubmed/37894144
http://dx.doi.org/10.3390/microorganisms11102486

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