Cargando…

Mutation Analysis in Regulator DNA-Binding Regions for Antimicrobial Efflux Pumps in 17,000 Pseudomonas aeruginosa Genomes

Mutations leading to upregulation of efflux pumps can produce multiple drug resistance in the pathogen Pseudomonas aeruginosa. Changes in their DNA binding regions, i.e., palindromic operators, can compromise pump depression and subsequently enhance resistance against several antibacterials and bioc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pérez-Vázquez, María, López-Causapé, Carla, Corral-Lugo, Andrés, McConnell, Michael J., Oteo-Iglesias, Jesús, Oliver, Antonio, Martín-Galiano, Antonio J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609311/ https://www.ncbi.nlm.nih.gov/pubmed/37894144 http://dx.doi.org/10.3390/microorganisms11102486

Ejemplares similares

Cataract Extraction: Notes on 17,000 Operations
por: Macphail, James M.
Publicado: (1925)

Low Ciprofloxacin Concentrations Select Multidrug-Resistant Mutants Overproducing Efflux Pumps in Clinical Isolates of Pseudomonas aeruginosa
por: Sanz-García, Fernando, et al.
Publicado: (2022)

Role of Efflux Pumps on Antimicrobial Resistance in Pseudomonas aeruginosa
por: Lorusso, Andre Bittencourt, et al.
Publicado: (2022)

The allelic spectrum of Charcot–Marie–Tooth disease in over 17,000 individuals with neuropathy
por: DiVincenzo, Christina, et al.
Publicado: (2014)

Evaluation of Heterocyclic Carboxamides as Potential Efflux Pump Inhibitors in Pseudomonas aeruginosa
por: Yuan, Yi, et al.
Publicado: (2021)

Interaction of antibacterial compounds with RND eﬄux pumps in Pseudomonas aeruginosa
por: Dreier, Jürg, et al.
Publicado: (2015)

Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence
por: Rampioni, Giordano, et al.
Publicado: (2017)

Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
Publicado: (2019)

Identification of Promoter Region Markers Associated With Altered Expression of Resistance-Nodulation-Division Antibiotic Efflux Pumps in Acinetobacter baumannii
por: López-Siles, Mireia, et al.
Publicado: (2022)

The Versatile Mutational Resistome of Pseudomonas aeruginosa
por: López-Causapé, Carla, et al.
Publicado: (2018)

Spread of Efflux Pump Overexpressing-Mediated Fluoroquinolone Resistance and Multidrug Resistance in Pseudomonas aeruginosa by using an Efflux Pump Inhibitor
por: Adabi, Maryam, et al.
Publicado: (2015)

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa
por: Verchère, Alice, et al.
Publicado: (2014)

Identification of Efflux Pump Mutations in Pseudomonas aeruginosa from Clinical Samples
por: Quddus, Sonia, et al.
Publicado: (2023)

Evaluation of a Conformationally Constrained Indole Carboxamide as a Potential Efflux Pump Inhibitor in Pseudomonas aeruginosa
por: Zhang, Yongzheng, et al.
Publicado: (2022)

Mycobacterium tuberculosis Complex Lipid Virulence Factors Preserved in the 17,000-Year-Old Skeleton of an Extinct Bison, Bison antiquus
por: Lee, Oona Y-C., et al.
Publicado: (2012)

Three Groups in the 28 Joints for Rheumatoid Arthritis Synovitis – Analysis Using More than 17,000 Assessments in the KURAMA Database
por: Terao, Chikashi, et al.
Publicado: (2013)

Risk Categories in COVID-19 Based on Degrees of Inflammation: Data on More Than 17,000 Patients from the Spanish SEMI-COVID-19 Registry
por: Rubio-Rivas, Manuel, et al.
Publicado: (2021)

Efflux pump inhibitors (EPIs) as new antimicrobial agents against Pseudomonas aeruginosa
por: Askoura, Momen, et al.
Publicado: (2011)

Overexpression of Efflux Pump in Multiresistant Pseudomonas aeruginosa: How You Will Discover and Treat It?
por: Koo, Sun Hoe
Publicado: (2015)

Conessine as a novel inhibitor of multidrug efflux pump systems in Pseudomonas aeruginosa
por: Siriyong, Thanyaluck, et al.
Publicado: (2017)

Detection of Overexpression of Efflux Pump Expression in Fluoroquinolone-Resistant Pseudomonas aeruginosa Isolates
por: Al Rashed, Nouf, et al.
Publicado: (2020)

Reduced Efflux Pumps Expression of Pseudomonas Aeruginosa with Satureja Khuzistanica Essential Oil
por: Iman Islamieh, Davoud, et al.
Publicado: (2020)

Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump
por: Gervasoni, Silvia, et al.
Publicado: (2023)

The Impact of an Efflux Pump Inhibitor on the Activity of Free and Liposomal Antibiotics against Pseudomonas aeruginosa
por: Gbian, Douweh Leyla, et al.
Publicado: (2021)

Using a Concept Inventory to Assess the Reasoning Component of Citizen-Level Science Literacy: Results from a 17,000-Student Study
por: Nuhfer, Edward B., et al.
Publicado: (2016)

Happier during lockdown: a descriptive analysis of self-reported wellbeing in 17,000 UK school students during Covid-19 lockdown
por: Soneson, Emma, et al.
Publicado: (2022)

Evaluation of efflux pumps gene expression in resistant Pseudomonas aeruginosa isolates in an Iranian referral hospital
por: Pourakbari, Babak, et al.
Publicado: (2016)

MexAB-OprM Efflux Pump Interaction with the Peptidoglycan of Escherichia coli and Pseudomonas aeruginosa
por: Ma, Miao, et al.
Publicado: (2021)

Insilico Functional Analysis of Genome-Wide Dataset From 17,000 Individuals Identifies Candidate Malaria Resistance Genes Enriched in Malaria Pathogenic Pathways
por: Damena, Delesa, et al.
Publicado: (2021)

Inhaled corticosteroid dose is associated with Pseudomonas aeruginosa infection in severe COPD
por: Shafiek, Hanaa, et al.
Publicado: (2021)

Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures
por: Housseini B Issa, Karim, et al.
Publicado: (2018)

Pseudomonas aeruginosa mexR and mexEF Antibiotic Efflux Pump Variants Exhibit Increased Virulence
por: Vaillancourt, Mylene, et al.
Publicado: (2021)

Advanced transcriptomic analysis reveals the role of efflux pumps and media composition in antibiotic responses of Pseudomonas aeruginosa
por: Rajput, Akanksha, et al.
Publicado: (2022)

Safety of Ixekizumab Treatment for up to 5 Years in Adult Patients with Moderate-to-Severe Psoriasis: Results from Greater Than 17,000 Patient-Years of Exposure
por: Armstrong, April, et al.
Publicado: (2019)

Pseudomonas aeruginosa antibiotic susceptibility profiles, genomic epidemiology and resistance mechanisms: a nation-wide five-year time lapse analysis
por: Sastre-Femenia, Miquel Àngel, et al.
Publicado: (2023)

Increased fluoroquinolone resistance with time in Escherichia coli from >17,000 patients at a large county hospital as a function of culture site, age, sex, and location
por: Boyd, Lauren Becnel, et al.
Publicado: (2008)

Body roundness index is a superior indicator to associate with the cardio‐metabolic risk: evidence from a cross‐sectional study with 17,000 Eastern-China adults
por: Xu, Jinjian, et al.
Publicado: (2021)

Two-component regulatory systems in Pseudomonas aeruginosa: an intricate network mediating fimbrial and efflux pump gene expression
por: Sivaneson, Melissa, et al.
Publicado: (2011)

Role of the Multidrug Resistance Efflux Pump MexCD-OprJ in the Pseudomonas aeruginosa Quorum Sensing Response
por: Alcalde-Rico, Manuel, et al.
Publicado: (2018)

Effect of Titanium Dioxide Nanoparticles on the Expression of Efflux Pump and Quorum-Sensing Genes in MDR Pseudomonas aeruginosa Isolates
por: Ahmed, Fatma Y., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qk4dvbburr7eufh1gerqh131bv