Telomerase inhibitors TMPyP4 and thymoquinone decreased cell proliferation and induced cell death in the non-small cell lung cancer cell line LC-HK2, modifying the pattern of focal adhesion

G‐quadruplexes (G4) are structures formed at the ends of telomeres rich in guanines and stabilized by molecules that bind to specific sites. TMPyP4 and thymoquinone (TQ) are small molecules that bind to G4 and have drawn attention because of their role as telomerase inhibitors. The aim of this study...

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Detalles Bibliográficos
Autores principales: Garnique, A.M.B., Rezende-Teixeira, P., Machado‐Santelli, G.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609552/
https://www.ncbi.nlm.nih.gov/pubmed/37909496
http://dx.doi.org/10.1590/1414-431X2023e12897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609552/
https://www.ncbi.nlm.nih.gov/pubmed/37909496
http://dx.doi.org/10.1590/1414-431X2023e12897

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