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Challenges in Permeability Assessment for Oral Drug Product Development

Drug permeation across the intestinal epithelium is a prerequisite for successful oral drug delivery. The increased interest in oral administration of peptides, as well as poorly soluble and poorly permeable compounds such as drugs for targeted protein degradation, have made permeability a key param...

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Detalles Bibliográficos
Autores principales: Koziolek, Mirko, Augustijns, Patrick, Berger, Constantin, Cristofoletti, Rodrigo, Dahlgren, David, Keemink, Janneke, Matsson, Pär, McCartney, Fiona, Metzger, Marco, Mezler, Mario, Niessen, Janis, Polli, James E., Vertzoni, Maria, Weitschies, Werner, Dressman, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609725/
https://www.ncbi.nlm.nih.gov/pubmed/37896157
http://dx.doi.org/10.3390/pharmaceutics15102397