Complexes of Ibuprofen Thiazolidin-4-One Derivatives with β-Cyclodextrin: Characterization and In Vivo Release Profile and Biological Evaluation

Generally, NSAIDs are weakly soluble in water and contain both hydrophilic and hydrophobic groups. One of the most widely used NSAIDs is ibuprofen, which has a poor solubility and high permeability profile. By creating dynamic, non-covalent, water-soluble inclusion complexes, cyclodextrins (CDs) can...

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Detalles Bibliográficos
Autores principales: Vasincu, Ioana Mirela, Apotrosoaei, Maria, Lupascu, Florentina, Iacob, Andreea-Teodora, Giusca, Simona-Eliza, Caruntu, Irina-Draga, Marangoci, Narcisa-Laura, Petrovici, Anca Roxana, Stanciu, Gabriela Dumitrita, Tamba, Bogdan-Ionel, Profire, Bianca-Stefania, Focsa, Alin-Viorel, Pinteala, Mariana, Profire, Lenuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609741/
https://www.ncbi.nlm.nih.gov/pubmed/37896252
http://dx.doi.org/10.3390/pharmaceutics15102492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609741/
https://www.ncbi.nlm.nih.gov/pubmed/37896252
http://dx.doi.org/10.3390/pharmaceutics15102492

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