Collagenase-Responsive Hydrogel Loaded with GSK2606414 Nanoparticles for Periodontitis Treatment through Inhibiting Inflammation-Induced Expression of PERK of Periodontal Ligament Stem Cells

GSK2606414 is a new, effective, highly selective PERK inhibitor with adenosine-triphosphate-competitive characteristics. It can inhibit endoplasmic reticulum stress and has the possibility of treating periodontitis. However, owing to its strong hydrophobicity and side effects, highly efficient pharm...

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Detalles Bibliográficos
Autores principales: Zhou, Yuchen, Liu, Jie, Xue, Peng, Zhang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609791/
https://www.ncbi.nlm.nih.gov/pubmed/37896262
http://dx.doi.org/10.3390/pharmaceutics15102503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609791/
https://www.ncbi.nlm.nih.gov/pubmed/37896262
http://dx.doi.org/10.3390/pharmaceutics15102503

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