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Investigation of the Impact of Saccharides on the Relative Activity of Trypsin and Catalase after Droplet and Spray Drying

While using saccharides as stabilizers for therapeutic protein drying is common, the mechanisms underlying the stabilization during drying remain largely unexplored. Herein, we investigated the effect of different saccharides, trehalose dihydrate (TD), dextran (DEX), and hydroxypropyl β-cyclodextrin...

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Detalles Bibliográficos
Autores principales: Dieplinger, Johanna, Moser, Christina, König, Gerhard, Pinto, Joana T., Paudel, Amrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609839/
https://www.ncbi.nlm.nih.gov/pubmed/37896264
http://dx.doi.org/10.3390/pharmaceutics15102504