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A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence

The Eph kinases are the largest receptor tyrosine kinases (RTKs) family in humans. PC3 human prostate adenocarcinoma cells are a well-established model for studying Eph–ephrin pharmacology as they naturally express a high level of EphA2, a promising target for new cancer therapies. A pharmacological...

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Detalles Bibliográficos
Autores principales: Festuccia, Claudio, Corrado, Miriam, Rossetti, Alessandra, Castelli, Riccardo, Lodola, Alessio, Gravina, Giovanni Luca, Tognolini, Massimiliano, Giorgio, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609876/
https://www.ncbi.nlm.nih.gov/pubmed/37895923
http://dx.doi.org/10.3390/ph16101452