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Analysis of miRNAs in Osteogenesis imperfecta Caused by Mutations in COL1A1 and COL1A2: Insights into Molecular Mechanisms and Potential Therapeutic Targets

Osteogenesis imperfecta (OI) is a group of connective tissue disorders leading to abnormal bone formation, mainly due to mutations in genes encoding collagen type I (Col I). Osteogenesis is regulated by a number of molecules, including microRNAs (miRNAs), indicating their potential as targets for OI...

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Detalles Bibliográficos
Autores principales: Botor, Malwina, Auguściak-Duma, Aleksandra, Lesiak, Marta, Sieroń, Łukasz, Dziedzic-Kowalska, Agata, Witecka, Joanna, Asman, Marek, Madetko-Talowska, Anna, Bik-Multanowski, Mirosław, Galicka, Anna, Sieroń, Aleksander L., Gawron, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609877/
https://www.ncbi.nlm.nih.gov/pubmed/37895885
http://dx.doi.org/10.3390/ph16101414