Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug–Drug Interactions of Phenytoin

Regulatory agencies worldwide expect that clinical pharmacokinetic drug–drug interactions (DDIs) between an investigational new drug and other drugs should be conducted during drug development as part of an adequate assessment of the drug’s safety and efficacy. However, it is neither time nor cost e...

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Detalles Bibliográficos
Autores principales: Rodriguez-Vera, Leyanis, Yin, Xuefen, Almoslem, Mohammed, Romahn, Karolin, Cicali, Brian, Lukacova, Viera, Cristofoletti, Rodrigo, Schmidt, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609929/
https://www.ncbi.nlm.nih.gov/pubmed/37896246
http://dx.doi.org/10.3390/pharmaceutics15102486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609929/
https://www.ncbi.nlm.nih.gov/pubmed/37896246
http://dx.doi.org/10.3390/pharmaceutics15102486

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