Saquinavir-Piperine Eutectic Mixture: Preparation, Characterization, and Dissolution Profile

The dissolution rate of the anti-HIV drug saquinavir base (SQV), a poorly water-soluble and extremely low absolute bioavailability drug, was improved through a eutectic mixture formation approach. A screening based on a liquid-assisted grinding technique was performed using a 1:1 molar ratio of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Fandaruff, Cinira, Quirós-Fallas, María Isabel, Vega-Baudrit, José Roberto, Navarro-Hoyos, Mirtha, Lamas, Diego German, Araya-Sibaja, Andrea Mariela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609941/
https://www.ncbi.nlm.nih.gov/pubmed/37896206
http://dx.doi.org/10.3390/pharmaceutics15102446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609941/
https://www.ncbi.nlm.nih.gov/pubmed/37896206
http://dx.doi.org/10.3390/pharmaceutics15102446

Ejemplares similares