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Saquinavir-Piperine Eutectic Mixture: Preparation, Characterization, and Dissolution Profile
The dissolution rate of the anti-HIV drug saquinavir base (SQV), a poorly water-soluble and extremely low absolute bioavailability drug, was improved through a eutectic mixture formation approach. A screening based on a liquid-assisted grinding technique was performed using a 1:1 molar ratio of the...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609941/ https://www.ncbi.nlm.nih.gov/pubmed/37896206 http://dx.doi.org/10.3390/pharmaceutics15102446 |