Molecular Mechanisms Involved in the Chemical Instability of ONC201 and Methods to Counter Its Degradation in Solution

Glioblastoma is one of the most common and aggressive forms of brain tumor, a rare disease for which there is a great need for innovative therapies. ONC201, a new drug substance, has been used in a compassionate treatment program where the choice of dosage form and regimen have yet to be justified....

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Detalles Bibliográficos
Autores principales: Annereau, Maxime, Vignes, Marina, Denis, Lucas, Rieutord, André, Legrand, François-Xavier, Rioblanc, François, Paul, Muriel, Grill, Jacques, Secretan, Philippe-Henri, Do, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609984/
https://www.ncbi.nlm.nih.gov/pubmed/37896134
http://dx.doi.org/10.3390/pharmaceutics15102371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609984/
https://www.ncbi.nlm.nih.gov/pubmed/37896134
http://dx.doi.org/10.3390/pharmaceutics15102371

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