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Amphipathic Cell-Penetrating Peptide-Aided Delivery of Cas9 RNP for In Vitro Gene Editing and Correction

The therapeutic potential of the CRISPR-Cas9 gene editing system in treating numerous genetic disorders is immense. To fully realize this potential, it is crucial to achieve safe and efficient delivery of CRISPR-Cas9 components into the nuclei of target cells. In this study, we investigated the appl...

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Detalles Bibliográficos
Autores principales: Öktem, Mert, Mastrobattista, Enrico, de Jong, Olivier G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609989/
https://www.ncbi.nlm.nih.gov/pubmed/37896260
http://dx.doi.org/10.3390/pharmaceutics15102500