Process to Remove the Size Variants Contained in the Antibody–Chelator Complex PCTA-NCAB001 for Radiolabeling with Copper-64

Understanding the physicochemical properties of antibody–drug conjugates is critical to assess their quality at manufacturing and monitor them during subsequent storage. For radiometal–antibody complexes, it is important to control the properties of the antibody–chelator conjugate to maintain the qu...

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Detalles Bibliográficos
Autores principales: Yoshii, Yukie, Matsumoto, Hiroki, Igarashi, Chika, Tachibana, Tomoko, Hihara, Fukiko, Shinada, Mitsuhiro, Waki, Atsuo, Yoshida, Sei, Naito, Kenichiro, Ito, Kimiteru, Higashi, Tatsuya, Kurihara, Hiroaki, Ueno, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610008/
https://www.ncbi.nlm.nih.gov/pubmed/37895812
http://dx.doi.org/10.3390/ph16101341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610008/
https://www.ncbi.nlm.nih.gov/pubmed/37895812
http://dx.doi.org/10.3390/ph16101341

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