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Soloxolone Methyl Reduces the Stimulatory Effect of Leptin on the Aggressive Phenotype of Murine Neuro2a Neuroblastoma Cells via the MAPK/ERK1/2 Pathway

Despite the proven tumorigenic effect of leptin on epithelial-derived cancers, its impact on the aggressiveness of neural crest-derived cancers, notably neuroblastoma, remains largely unexplored. In our study, for the first time, transcriptome analysis of neuroblastoma tissue demonstrated that the l...

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Detalles Bibliográficos
Autores principales: Odarenko, Kirill V., Salomatina, Oksana V., Chernikov, Ivan V., Salakhutdinov, Nariman F., Zenkova, Marina A., Markov, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610011/
https://www.ncbi.nlm.nih.gov/pubmed/37895840
http://dx.doi.org/10.3390/ph16101369