Efficacy of Apremilast Gels in Mouse Model of Imiquimod-Induced Psoriasis Skin Inflammation

Apremilast (APM) is a novel drug for the treatment of psoriasis and psoriatic arthritis. APM is a phosphodiesterase 4 (PDE4) inhibitor, raising intracellular cAMP levels and thereby decreasing the inflammatory response by modulating the expression of TNF-α, IL-17, IL-23, and other inflammatory cytok...

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Detalles Bibliográficos
Autores principales: Silva-Abreu, Marcelle, Sosa, Lilian, Espinoza, Lupe Carolina, Fábrega, María-José, Rodríguez-Lagunas, María J., Mallandrich, Mireia, Calpena, Ana Cristina, Garduño-Ramírez, María Luisa, Rincón, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610068/
https://www.ncbi.nlm.nih.gov/pubmed/37896163
http://dx.doi.org/10.3390/pharmaceutics15102403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610068/
https://www.ncbi.nlm.nih.gov/pubmed/37896163
http://dx.doi.org/10.3390/pharmaceutics15102403

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