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The Synthetic Peptide GA-Hecate and Its Analogs Inhibit Multiple Steps of the Chikungunya Virus Infection Cycle In Vitro

Chikungunya virus (CHIKV) belongs to the Alphavirus genus and is responsible for significant outbreaks worldwide. Currently, there is no approved antiviral therapy against CHIKV. Bioactive peptides have great potential for new drug development. Here, we evaluated the antiviral activity of the synthe...

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Detalles Bibliográficos
Autores principales: Ayusso, Gabriela Miranda, da Silva Sanches, Paulo Ricardo, Carvalho, Tamara, Santos, Igor Andrade, Martins, Daniel Oliveira Silva, Lima, Maria Letícia Duarte, da Conceição, Pâmela Jóyce Previdelli, Bittar, Cíntia, Merits, Andres, Cilli, Eduardo Maffud, Jardim, Ana Carolina Gomes, Rahal, Paula, Calmon, Marilia Freitas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610090/
https://www.ncbi.nlm.nih.gov/pubmed/37895860
http://dx.doi.org/10.3390/ph16101389