Cargando…
The Synthetic Peptide GA-Hecate and Its Analogs Inhibit Multiple Steps of the Chikungunya Virus Infection Cycle In Vitro
Chikungunya virus (CHIKV) belongs to the Alphavirus genus and is responsible for significant outbreaks worldwide. Currently, there is no approved antiviral therapy against CHIKV. Bioactive peptides have great potential for new drug development. Here, we evaluated the antiviral activity of the synthe...
Autores principales: | Ayusso, Gabriela Miranda, da Silva Sanches, Paulo Ricardo, Carvalho, Tamara, Santos, Igor Andrade, Martins, Daniel Oliveira Silva, Lima, Maria Letícia Duarte, da Conceição, Pâmela Jóyce Previdelli, Bittar, Cíntia, Merits, Andres, Cilli, Eduardo Maffud, Jardim, Ana Carolina Gomes, Rahal, Paula, Calmon, Marilia Freitas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610090/ https://www.ncbi.nlm.nih.gov/pubmed/37895860 http://dx.doi.org/10.3390/ph16101389 |
Ejemplares similares
-
The Dimeric Peptide (KKYRYHLKPF)(2)K Shows Broad-Spectrum Antiviral Activity by Inhibiting Different Steps of Chikungunya and Zika Virus Infection
por: Ayusso, Gabriela Miranda, et al.
Publicado: (2023) -
Antiviral Evaluation of New Synthetic Bioconjugates Based on GA-Hecate: A New Class of Antivirals Targeting Different Steps of Zika Virus Replication
por: da Silva Sanches, Paulo Ricardo, et al.
Publicado: (2023) -
GA-Hecate antiviral properties on HCV whole cycle represent a new antiviral class and open the door for the development of broad spectrum antivirals
por: Batista, Mariana Nogueira, et al.
Publicado: (2018) -
Recent advances in SARS-CoV-2 Spike protein and RBD mutations comparison between new variants Alpha (B.1.1.7, United Kingdom), Beta (B.1.351, South Africa), Gamma (P.1, Brazil) and Delta (B.1.617.2, India)
por: Sanches, Paulo R.S., et al.
Publicado: (2021) -
Burden of Influenza and Respiratory Syncytial Viruses in Suspected COVID-19 Patients: A Cross-Sectional and Meta-Analysis Study
por: da Costa, Vivaldo Gomes, et al.
Publicado: (2023)