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Small Molecule Cocktails Promote Fibroblast-to-Leydig-like Cell Conversion for Hypogonadism Therapy

Male hypogonadism arises from the inadequate production of testosterone (T) by the testes, primarily due to Leydig cell (LC) dysfunction. Small molecules possess several advantages, including high cell permeability, ease of synthesis, standardization, and low effective concentration. Recent investig...

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Detalles Bibliográficos
Autores principales: Yuan, Fei, Bai, Kaiping, Hou, Yanping, Zou, Xiangyu, Sun, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610100/
https://www.ncbi.nlm.nih.gov/pubmed/37896216
http://dx.doi.org/10.3390/pharmaceutics15102456