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Antiproliferative Imidazo-Pyrazole-Based Hydrogel: A Promising Approach for the Development of New Treatments for PLX-Resistant Melanoma

Aiming at developing a dermal formulation against melanoma, the synthesized imidazo-pyrazoles 2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylic acid (3-methoxy-4-phenoxy-benzylidene)-hydrazide (4G) and 2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylic acid (4-benzyloxy-3-methoxy-...

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Detalles Bibliográficos
Autores principales: Alfei, Silvana, Milanese, Marco, Brullo, Chiara, Valenti, Giulia Elda, Domenicotti, Cinzia, Russo, Eleonora, Marengo, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610107/
https://www.ncbi.nlm.nih.gov/pubmed/37896185
http://dx.doi.org/10.3390/pharmaceutics15102425