An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors

Non-structural protein 3 (nsp3) from all coronaviruses (CoVs) contains a conserved macrodomain, known as Mac1, that has been proposed as a potential therapeutic target for CoVs due to its critical role in viral pathogenesis. Mac1 is an ADP-ribose binding protein and ADP-ribosylhydrolase that promote...

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Detalles Bibliográficos
Autores principales: O’Connor, Joseph J., Ferraris, Dana, Fehr, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610136/
https://www.ncbi.nlm.nih.gov/pubmed/37887737
http://dx.doi.org/10.3390/pathogens12101221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610136/
https://www.ncbi.nlm.nih.gov/pubmed/37887737
http://dx.doi.org/10.3390/pathogens12101221

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